Bioactivity:

OSI-296 is a potent and dual inhibitor of cMET and RON kinases (IC50 value are 42 nM and 200 nM for cMet and sfRon respectively) . OSI-206 shows in vivo efficacy and is well tolerated in tumor xenografts models upon oral dosing. OSI-296 also reduces tumou

CAS nr:

1175296-94-2

Purity:

98%

Molecular Weight:

465,31

SMILES:

O=C(N1CC=C(C2=COC3=C2C=NC(N)=C3O[C@@H](C4=C(Cl)C=CC(F)=C4Cl)C)CC1)N

Formula:

C21H19Cl2FN4O3

Pathway:

Target: