Bioactivity:

Cilengitide is a potent integrin inhibitor for the _v_3/5 receptor (IC50: 4.1/79 nM, in cell-free assays); ~10-fold selectivity against gpIIbIIIa.

CAS nr:

188968-51-6

Purity:

98%

Molecular Weight:

588,66

SMILES:

CC(C)[C@@H]1N(C)C(=O)[C@@H](Cc2ccccc2)NC(=O)[C@H](CC(O)=O)NC(=O)CNC(=O)[C@H](CCCNC(N)=N)NC1=O

Formula:

C27H40N8O7

Pathway:

Cytoskeletal Signaling,Autophagy

Target:

Integrin,Autophagy