Bioactivity:

KAG-308 is an effective selective and orally active agonist of the EP4 receptor (Ki: 2.57 nM and EC50: 17 nM for human EP4 receptor), more selective over EP1, EP2, EP3, and IP receptor. KAG-308 suppresses colitis and promotes histological mucosal healing,

CAS nr:

1215192-68-9

Purity:

98%

Molecular Weight:

460,52

SMILES:

O[C@H](C1)[C@H](/C=C/[C@@H](O)[C@@H](C2=CC=CC(C)=C2)C)[C@](C/3(F)F)([H])[C@@]1([H])OC3=C/CCCC4=NN=NN4

Formula:

C24H30F2N4O3

Pathway:

GPCR/G Protein,Immunology/Inflammation

Target:

Prostaglandin Receptor,Prostaglandin Receptor