Bioactivity:

HDACs/mTOR Inhibitor 1 is a dual HDACs and mammalian target of Rapamycin (mTOR) target inhibitor for treating hematologic malignancies (IC50s: 0.19 nM, 1.8 nM, 1.2 nM, and >500 nM for HDAC1, HDAC6, mTOR and PI3K_).

CAS nr:

2271413-06-8

Purity:

98%

Molecular Weight:

566,65

SMILES:

O=C(NO)CCCCCCN1C2=NC(C3=CC=C(NC(N4C[C@@H](C)OCC4)=O)C=C3)=NC(N5CCOCC5)=C2C=N1

Formula:

C28H38N8O5

Pathway:

DNA Damage/DNA Repair,Chromatin/Epigenetic

Target:

HDAC,HDAC