Bioactivity:

PHT-427 is a dual Akt (Ki: 2.7 _M) and PDPK1 (Ki: 5.2 _M) inhibitor (high-affinity binding for the PH domains of Akt and PDPK1).

CAS nr:

1191951-57-1

Purity:

98%

Molecular Weight:

409,61

SMILES:

CCCCCCCCCCCCc1ccc(cc1)S(=O)(=O)Nc1nncs1

Formula:

C20H31N3O2S2

Pathway:

Cytoskeletal Signaling,PI3K/Akt/mTOR signaling,Apoptosis,PI3K/Akt/mTOR signaling

Target:

Akt,Akt,Apoptosis,PDK