Bioactivity:

Isozyme-selective inhibitor of protein kinase C (PKC); competitively and reversibly inhibits PKC_I and PKC_II (IC50�values are 4.7 and 5.9 nM respectively). Selective for PKC_�over other PKC isozymes (IC50values are 0.052, 0.25, 0.30, 0.36, 0.60 and >100�

CAS nr:

169939-93-9

Purity:

98%

Molecular Weight:

505,01

SMILES:

CN(C)C[C@@H]1CCN2C=C(C3=CC=CC=C32)C4=C(C5=CN(CCO1)C6=CC=CC=C65)C(=O)NC4=O.Cl

Formula:

C28H28N4O3�HCl

Pathway:

Cytoskeletal Signaling,Chromatin/Epigenetic

Target:

PKC,PKC