CCT129202 T6435
Specifications
| 1mg/5mg/10mg/25mg/50mg/100mg |
Bioactivity:
CCT129202 is an ATP-competitive pan-Aurora inhibitor for Aurora A, Aurora B and Aurora C with IC50 of 0.042 _M, 0.198 _M and 0.227 _M, respectively. It is less potent to FGFR3, GSK3_, PDGFR_, etc.
CAS nr:
942947-93-5
Purity:
98%
Molecular Weight:
497,02
SMILES:
CN(C)c1ccc(cc1)-c1nc2ncc(Cl)c(N3CCN(CC(=O)Nc4nccs4)CC3)c2[nH]1
Formula:
C23H25ClN8OS
Pathway:
Chromatin/Epigenetic,Cell Cycle/Checkpoint
Target:
Aurora Kinase,Aurora Kinase
