Bioactivity:

A2B receptor antagonist 2 (compound 18) is an adenosine receptor A2B antagonist, with Ki values of 2.30 _M, 6.8 _M and 3.44 _M for rA1, rA2A and hA2B, respectively[1]. [1]. Thomas R Webb, et al. Quinazolines as adenosine receptor antagonists: SAR and selectivity for A2B receptors. Bioorg Med Chem. 2003 Jan 2;11(1):77-85.

CAS nr:

784-90-7

Purity:

98%

Molecular Weight:

229,287

SMILES:

Cc1cc2nc(NC(N)=N)nc(C)c2cc1C

Formula:

C12H15N5

Pathway:

GPCR/G Protein,Neuroscience

Target:

Adenosine Receptor,Adenosine Receptor