Bioactivity:

IDH1 Inhibitor 1�is an orally bioavailable, brain-penetrant, and selective mutant IDH1 inhibitor (IC50s: 0.021 _M, 0.045 _M, and 2.52 _M for IDH1R132H, IDH1R132C, and IDH1WT).

CAS nr:

2234285-81-3

Purity:

98%

Molecular Weight:

450,39

SMILES:

C[C@H](NC1=NC(N2[C@@H](CF)COC2=O)=CC=N1)C(N=C3)=CN3C4=CC=C(C(F)(F)F)C=C4

Formula:

C20H18F4N6O2

Pathway:

Others

Target:

Others