Bioactivity:

c-Fms-IN-9 is a c-FMS inhibitor extracted from patent WO2014145023A1 (Example 7). It inhibits unphosphorylated c-FMS kinase (uFMS) and uKIT (IC50s: <0.01 _M and 0.1-1 _M).

CAS nr:

1628574-50-4

Purity:

98%

Molecular Weight:

405,45

SMILES:

O=C1N(C2=NC(C)=C(OC3=CC(C4=CN(C)N=C4)=NC=C3)C=C2)NC(C(C)(C)C)=N1

Formula:

C21H23N7O2

Pathway:

Tyrosine Kinase/Adaptors

Target:

c-Fms