Bioactivity:

PP2 is a effective inhibitor of Lck/Fyn (IC50:4/5 nM) , ~100-fold less potent to EGFR, inactive for ZAP-70, PKA and JAK2.

CAS nr:

172889-27-9

Purity:

98%

Molecular Weight:

301,77

SMILES:

CC(C)(C)n1c2c(c(n1)c1ccc(cc1)Cl)c(ncn2)N

Formula:

C15H16ClN5

Pathway:

Chromatin/Epigenetic,Stem Cells,Angiogenesis,JAK/STAT signaling,Tyrosine Kinase/Adaptors,Angiogenesis,Tyrosine Kinase/Adaptors,Angiogenesis,JAK/STAT signaling,Tyrosine Kinase/Adaptors

Target:

JAK,JAK,JAK,JAK,Src,Src,EGFR,EGFR,EGFR,Tyrosine Kinases