Bioactivity:

ML323 is a reversible and effective USP1-UAF1 inhibitor in a Ub-Rho assay (IC50: 76 nM) and in orthogonal gel-based assays using K63-linked diubiquitin (di-Ub) (IC50: 174 nM 820 nM)and monoubiquitinated PCNA (Ub-PCNA) (IC50: 820 nM) as substrates, respect

CAS nr:

1572414-83-5

Purity:

98%

Molecular Weight:

384,48

SMILES:

CC(C)c1ccccc1-c1ncc(C)c(NCc2ccc(cc2)-n2ccnn2)n1

Formula:

C23H24N6

Pathway:

Ubiquitination,Cell Cycle/Checkpoint,DNA Damage/DNA Repair

Target:

DUB,DUB,DUB