Bioactivity:

Toyocamycin is an adenosine analog produced by Actinomycete, acts as an XBP1 inhibitor, inhibits IRE1_-induced ATP-dependent XBP1 mRNA cleavage (IC50: 80 nM). Toyocamycin induces apoptosis.

CAS nr:

606-58-6

Purity:

98%

Molecular Weight:

291,26

SMILES:

O[C@H]1[C@@H](O[C@H](CO)[C@H]1O)N2C3=C(C(N)=NC=N3)C(C#N)=C2

Formula:

C12H13N5O4

Pathway:

Microbiology/Virology,Microbiology/Virology,Others,Cell Cycle/Checkpoint,Apoptosis

Target:

Antifungal,Antibiotic,Others,IRE1,Apoptosis