Bioactivity:

Temsirolimus is a specific mTOR inhibitor ( IC50: 1.76 _M), used in the treatment of advanced renal cell cancer.

CAS nr:

162635-04-3

Purity:

98%

Molecular Weight:

1030,29

SMILES:

CO[C@@H]1C[C@H](C[C@@H](C)[C@@H]2CC(=O)[C@H](C)\C=C(C)\[C@@H](O)[C@@H](OC)C(=O)[C@H](C)C[C@H](C)\C=C/C=C/C=C(C)/[C@H](C[C@@H]3CC[C@@H](C)[C@@](O)(O3)C(=O)C(=O)N3CCCC[C@H]3C(=O)O2)OC)CC[C@H]1OC(=O)C(C)(CO)CO

Formula:

C56H87NO16

Pathway:

PI3K/Akt/mTOR signaling,Autophagy,Apoptosis

Target:

mTOR,Autophagy,Apoptosis