Bioactivity:

(Rac)-BRD0705 is a less active racemate of BRD0705. BRD0705 is a potent, paralog selective and orally active inhibitor of GSK3_ (IC50 of 66 nM and a Kd of 4.8 _M). BRD0705 displays increased selectivity for GSK3_ (8-fold) versus GSK3_ (IC50 of 515 nM).

CAS nr:

1597440-03-3

Purity:

98%

Molecular Weight:

321,42

SMILES:

O=C1C2=C(N=C3C(C2(CC)C4=CC=CC=C4)=CNN3)CC(C)(C)C1

Formula:

C20H23N3O

Pathway:

Others

Target:

Others