Bioactivity:

Taltirelin acetate is a superagonist at thyrotropin-releasing hormone receptor (TRH-R)(IC50 of 910 nM and EC50 of 36 nM for stimulating an increase in cytosolic Ca2+ concentration (Ca2+ release)).

CAS nr:

1549593-23-8

Purity:

98%

Molecular Weight:

465,46

SMILES:

O=C(N(CCC1)[C@@H]1C(N)=O)[C@@H](NC([C@@H](NC2=O)CC(N2C)=O)=O)CC3=CN=CN3.CC(O)=O

Formula:

C19H27N7O7

Pathway:

Endocrinology/Hormones

Target:

Thyroid hormone receptor(THR)