Bioactivity:

M8891 is an orally active, reversible and brain penetrant Methionine Aminopeptidase-2 (MetAP-2) inhibitor(IC50 :54nM;Ki:4.33 nM).M8891 inhibits growth of primary endothelial cells as well as tumor cells and demonstrates antiangiogenic and antitumoral acti

CAS nr:

1464842-09-8

Purity:

98%

Molecular Weight:

385,36

SMILES:

O=C([C@]1(O)C(N(C2=CC3=C(NC=C3)C=C2)CC1)=O)NCC4=CC(F)=CC(F)=C4

Formula:

C20H17F2N3O3

Pathway:

Others

Target:

Others