Bioactivity:

MK-4827 racemate is a selective inhibitor of PARP1/2 (IC50: 3.8 nM/2.1 nM). It >330-fold selective against PARP3, V-PARP and Tank1.

CAS nr:

1038915-75-1

Purity:

98%

Molecular Weight:

320,39

SMILES:

N=C(O)C1=CC=CC(C1=N2)=CN2C3=CC=C(C4CCCNC4)C=C3

Formula:

C19H20N4O

Pathway:

Chromatin/Epigenetic,DNA Damage/DNA Repair

Target:

PARP,PARP