Bioactivity:

FT827 is a selective and covalent inhibitor of ubiquitin-specific protease 7 (USP7) (Ki: 4.2 ﾵM). FT827 binds to the USP7 catalytic domain (apparent Kd: 7.8 ﾵM).

CAS nr:

1959537-86-0

Purity:

98%

Molecular Weight:

548,61

SMILES:

C=CS(=O)(NC1=CC=CC=C1C2=CC=C(C(N3CCC(O)(CN(C=NC4=C5C=NN4C)C5=O)CC3)=O)C=C2)=O

Formula:

C27H28N6O5S

Pathway:

Ubiquitination,Cell Cycle/Checkpoint,DNA Damage/DNA Repair

Target:

DUB,DUB,DUB