Bioactivity:

A 839977 is a P2X7 selective antagonist and the antihyperalgesic effects of P2X7 receptor blockade are mediated by blocking the release of IL-1beta[1]. It blocks BzATP-evoked calcium influx at recombinant human, rat and mouse P2X7 receptors (IC50 values a

CAS nr:

870061-27-1

Purity:

98%

Molecular Weight:

413,26

SMILES:

ClC1=C(Cl)C(N2N=NN=C2NCC3=CC=CC=C3OC4=NC=CC=C4)=CC=C1

Formula:

C19H14Cl2N6O

Pathway:

Neuroscience

Target:

P2 Receptor