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Bioactivity:
Kira8 is a mono-selective IRE1_ inhibitor that allosterically attenuates IRE1_ RNase activity (IC50: 5.9 nM).
CAS nr:
1630086-20-2
Purity:
98%
Molecular Weight:
601,12
SMILES:
O=S(C1=CC=CC=C1Cl)(NC2=C3C=CC(C)=C(OC4=NC=CC=C4C5=NC(N[C@@H]6CNCCC6)=NC=C5)C3=CC=C2)=O
Formula:
C31H29ClN6O3S
Pathway:
Cell Cycle/Checkpoint
Target:
IRE1