Bioactivity:

Go6976 is a potent PKC inhibitor with IC50 of 7.9 nM, 2.3 nM, and 6.2 nM for PKC (Rat brain), PKC_, and PKC_1, respectively. Also a potent inhibitor of JAK2 and Flt3.

CAS nr:

136194-77-9

Purity:

98%

Molecular Weight:

377,42

SMILES:

CN1C2=C(C=CC=C2)C2=C1C1=C(C3=C2C(=O)NC3)C2=C(C=CC=C2)N1CCC#N

Formula:

C24H18N4O

Pathway:

Angiogenesis,Tyrosine Kinase/Adaptors,Chromatin/Epigenetic,Stem Cells,Angiogenesis,JAK/STAT signaling,Microbiology/Virology,Cytoskeletal Signaling,Chromatin/Epigenetic

Target:

FLT,FLT,JAK,JAK,JAK,JAK,Influenza Virus,PKC,PKC