Bioactivity:

ExcisaninA may be a potent inhibitor of AKT signaling pathway in tumor cells, it can inhibit invasion by suppressing MMP-2 and MMP-9 expression, it may be a potential anti-metastatic chemotherapeutic agent for the treatment of breast cancer. Excisanin A s

CAS nr:

78536-37-5

Purity:

98%

Molecular Weight:

350,44

SMILES:

CC1(C)CC[C@H](O)[C@@]2(C)[C@@H]3C[C@H](O)[C@@H]4[C@@H](O)[C@@]3([C@H](O)C[C@H]12)C(=O)C4=C

Formula:

C20H30O5

Pathway:

Stem Cells,Proteases/Proteasome,Apoptosis,PI3K/Akt/mTOR signaling,MAPK,DNA Damage/DNA Repair,Chromatin/Epigenetic,GPCR/G Protein,Immunology/Inflammation,Proteases/Proteasome,Stem Cells,PI3K/Akt/mTOR signaling,Cytoskeletal Signaling,PI3K/Akt/mTOR signaling,NF-_b,Angiogenesis,Tyrosine Kinase/Adaptors,Cytoskeletal Signaling,Cytoskeletal Signaling

Target:

Wnt/beta-catenin,Caspase,Caspase,PI3K,JNK,PARP,PARP,Prostaglandin Receptor,Prostaglandin Receptor,MMP,GSK-3,GSK-3,Akt,Akt,NF-_B,FAK,FAK,FAK,Wnt/beta-catenin