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TargetMol Chemicals

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TargetMol Chemicals Inc. specializes in products and services that serve the research needs of chemical and biological scientists worldwide. With a client base in 40+ countries, TargetMol has evolved into one of the biggest global research suppliers for compound libraries and small molecule compounds.

TargetMol diligently updates and offers over 170 types of compound libraries and a wide range of high-quality research chemicals, including inhibitors, activators, natural products, peptides, antibodies , and novel life-science kits for laboratory and scientific use. In addition, their lab allows them to conduct CADD (computer-aided drug design) and chemical synthesis to meet the customization needs of their clients.

With TargetMol’s high-quality products & services, fast & efficient global supply chain and professional technical support, TargetMol believes they will help you shorten your research process and yield a more successful result.

www.targetmol.com

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LY2811376 T2639

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Specifications

1mg/5mg/10mg/25mg/50mg/100mg

Bioactivity:

LY2811376, an orally available non-peptidic _-secretase(BACE1) inhibitor (IC50: 239-249 nM), can decrease A_ secretion (EC50: 300 nM). It has 10-fold selectivity towards BACE1 over BACE2, and more than 50-fold inhibition over other aspartic proteases incl

CAS nr:

1194044-20-6

Purity:

98%

Molecular Weight:

320,36

SMILES:

S1C(=N[C@](CC1)(C)c1c(cc(c(c1)c1cncnc1)F)F)N

Formula:

C15H14F2N4S

Pathway:

Neuroscience,Neuroscience,Neuroscience

Target:

Beta-Secretase,Beta Amyloid,BACE