Bioactivity:

AT7519 is a CDK1/2/4/6/9 inhibitor (IC50: 10-210 nM). It is less effective to CDK3 and little active to CDK7.

CAS nr:

844442-38-2

Purity:

98%

Molecular Weight:

382,24

SMILES:

Clc1cccc(Cl)c1C(=O)Nc1cn[nH]c1C(=O)NC1CCNCC1

Formula:

C16H17Cl2N5O2

Pathway:

PI3K/Akt/mTOR signaling,Stem Cells,Apoptosis,Cell Cycle/Checkpoint

Target:

GSK-3,GSK-3,Apoptosis,CDK