CL-387785 T2245
Specifications
| 1mg/5mg/10mg/25mg/50mg/100mg |
Bioactivity:
CL-387785(EKI785; WAY-EKI 785) is an irreversible inhibitor of EGFR_IC50_ 370+/-120 pM_; is able to overcome resistance caused by the T790M mutation on a functional level.
CAS nr:
194423-06-8
Purity:
98%
Molecular Weight:
381,23
SMILES:
CC#CC(=O)Nc1cc2c(cc1)ncnc2Nc1cc(ccc1)Br
Formula:
C18H13BrN4O
Pathway:
JAK/STAT signaling,Tyrosine Kinase/Adaptors,Angiogenesis
Target:
EGFR,EGFR,EGFR
