Bioactivity:

KGA-2727 is a potent and selective SGLT1 inhibitor, with Kis of 97.4 nM and 43.5 nM for human and rat SGLT1, respectively.�The selectivity ratios (Ki for SGLT2/Ki for SGLT1) of KGA-2727 are 140 (human) and 390 (rat).�KGA-2727 for the treatment of diabete.

CAS nr:

666842-36-0

Purity:

98%

Molecular Weight:

536,62

SMILES:

O=C(N)CCNCCCOC1=CC=C(CC2=C(C(C)C)NN=C2O[C@H]3[C@@H]([C@H]([C@@H]([C@@H](CO)O3)O)O)O)C(C)=C1

Formula:

C26H40N4O8

Pathway:

GPCR/G Protein

Target:

SGLT