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Toceranib T13178

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Specifications

size	1mg/5mg/10mg/25mg/50mg/100mg

Bioactivity:

Toceranib phosphate is an orally active inhibitor of tyrosine kinase (RTK) receptor, and it potently inhibits PDGFR, VEGFR, and Kit(with Kis of 5 and 6 nM for PDGFR_ and Flk-1/KDR, respectively), has antitumor and antiangiogenic activity.

CAS nr:

356068-94-5

Purity:

98%

Molecular Weight:

396,46

SMILES:

Cc1[nH]c(\C=C2/C(=O)Nc3ccc(F)cc23)c(C)c1C(=O)NCCN1CCCC1

Formula:

C22H25FN4O2

Pathway:

Angiogenesis,Tyrosine Kinase/Adaptors,Tyrosine Kinase/Adaptors,Angiogenesis,Tyrosine Kinase/Adaptors

Target:

PDGFR,PDGFR,VEGFR,VEGFR,c-Kit