Bioactivity:

AMG 837 was found to be a partial agonist on GPR40 with maximal activity 85% of that shown by DHA under our standard assay conditions. Overall, AMG 837 was both highly potent and selective in vitro. AMG 837 is a potent GPR40 agonist(EC50=13 nM) with a sup

CAS nr:

865231-46-5

Purity:

98%

Molecular Weight:

438,44

SMILES:

OC(C[C@H](C#CC)C1=CC=C(C=C1)OCC2=CC=CC(C3=CC=C(C(F)(F)F)C=C3)=C2)=O

Formula:

C26H21F3O3

Pathway:

Others

Target:

Others