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Bioactivity:
Asciminib (ABL001) is a potent and selective Bcr-Abl inhibitor (Kd: 0.5�0.8nM).
CAS nr:
1492952-76-7
Purity:
98%
Molecular Weight:
449,84
SMILES:
O[C@@H]1CCN(C1)c1ncc(cc1-c1ccn[nH]1)C(=O)Nc1ccc(OC(F)(F)Cl)cc1
Formula:
C20H18ClF2N5O3
Pathway:
Angiogenesis,Tyrosine Kinase/Adaptors,Cytoskeletal Signaling
Target:
Bcr-Abl,Bcr-Abl,Bcr-Abl