Bioactivity:

CID44216842 is a potent Cdc42-selective guanine nucleotide binding lead inhibitor.�The EC50s for Cdc42 WT and Cdc42Q61L mutant are 1.0 and 1.2 _M in GTP binding assay, respectively.�The EC50s for Cdc42 WT and Cdc42Q61L mutant are 0.3 and 0.5 _M in GDP bin

CAS nr:

1222513-26-9

Purity:

98%

Molecular Weight:

486,38

SMILES:

O=S(C1=CC=C(N2N=C(C3=CC=CC(OC)=C3)CC2C4=CC=C(Br)C=C4)C=C1)(N)=O

Formula:

C22H20BrN3O3S

Pathway:

MAPK,GPCR/G Protein,Cell Cycle/Checkpoint

Target:

Ras,Ras,CDK