Bioactivity:

Casopitant mesylate (GW679769B) is a selective, brain permeable, and orally active antagonist of neurokinin 1 (NK1) receptor. It is a second in the class of antiemetics.

CAS nr:

414910-30-8

Purity:

98%

Molecular Weight:

712,72

SMILES:

O=C(N1[C@@H](C2=CC=C(F)C=C2C)C[C@@H](N3CCN(C(C)=O)CC3)CC1)N([C@@H](C4=CC(C(F)(F)F)=CC(C(F)(F)F)=C4)C)C.CS(=O)(O)=O

Formula:

C31H39F7N4O5S

Pathway:

Metabolism,Neuroscience,GPCR/G Protein

Target:

P450,Neurokinin receptor,Neurokinin receptor