Bioactivity:

Through its effects on ULK1 and ULK2, MRT67307 blocks autophagy. MRT67307 prevents the phosphorylation of IRF3 and the production of IFN-_ and increases toll-like receptor-induced IL-10 and IL-1ra secretion in macrophages.�MRT67307 is a kinase inhibitor t

CAS nr:

1190378-57-4

Purity:

98%

Molecular Weight:

464,62

SMILES:

O=C(NCCCNc1nc(Nc2cccc(CN3CCOCC3)c2)ncc1C1CC1)C1CCC1

Formula:

C26H36N6O2

Pathway:

NF-_b,Autophagy

Target:

I_B/IKK,Autophagy