Bioactivity:

Resatorvid (TAK-242) is a selective inhibitor of Toll-like receptor 4 (TLR4). Resatorvid inhibits IL-6, TNF-R and NO production (IC50s: 1.3 nM, 1.9 nM, and 1.8 nM).

CAS nr:

243984-11-4

Purity:

98%

Molecular Weight:

361,82

SMILES:

O=S([C@H]1C(C(OCC)=O)=CCCC1)(NC2=CC=C(C=C2Cl)F)=O

Formula:

C15H17ClFNO4S

Pathway:

Apoptosis,Immunology/Inflammation,Immunology/Inflammation,Autophagy

Target:

TNF,Interleukin,TLR,Autophagy