Bioactivity:

ML-792 is a specific small ubiquitin-like modifier (SUMO)-activating enzyme (SAE) inhibitor. Compared with NAE/NEDD8 and UAE/ubiquitin (IC50s of 32 _M and >100 _M, respectively), ML-792 is an effective and selective inhibitor of SAE/SUMO1 and SAE/SUMO2 in

CAS nr:

1644342-14-2

Purity:

98%

Molecular Weight:

551,41

SMILES:

O=S(OC[C@@H]1[C@@H](O)C[C@H](NC2=NC=NC=C2C(C3=NN(CC4=CC=CC(Br)=C4)C=C3)=O)C1)(N)=O

Formula:

C21H23BrN6O5S

Pathway:

Ubiquitination

Target:

E1/E2/E3 Enzyme