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Bioactivity:
BAY1125976 is an allosteric inhibitor of Akt1 and Akt2 (IC50s of 5.2 and 18 nM, respectively, in a time-resolved FRET assay)
CAS nr:
1402608-02-9
Purity:
98%
Molecular Weight:
383,45
SMILES:
NC(=O)c1ccc2nc(c(-c3ccccc3)n2n1)-c1ccc(cc1)C1(N)CCC1
Formula:
C23H21N5O
Pathway:
Cytoskeletal Signaling,PI3K/Akt/mTOR signaling
Target:
Akt,Akt