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Bioactivity:
MK-1775 is a small molecule inhibitor of the checkpoint kinase WEE1 (IC50: 5.2 nM). It hinders the G2 DNA damage checkpoint.
CAS nr:
955365-80-7
Purity:
98%
Molecular Weight:
500,6
SMILES:
CN1CCN(CC1)c1ccc(Nc2ncc3c(n2)n(-c2cccc(n2)C(C)(C)O)n(CC=C)c3=O)cc1
Formula:
C27H32N8O2
Pathway:
Cell Cycle/Checkpoint
Target:
Wee1