Bioactivity:

BO-264 is a highly potent and orally active inhibitor of transforming acidic coiled-coil 3 (TACC3, IC50 of 188 nM and a Kd of 1.5 nM).

CAS nr:

2408648-20-2

Purity:

98%

Molecular Weight:

353,38

SMILES:

COC1=CC=C(C2=NOC(NC3=NC(N4CCOCC4)=NC=C3)=C2)C=C1

Formula:

C18H19N5O3

Pathway:

Tyrosine Kinase/Adaptors,Angiogenesis,Apoptosis

Target:

FGFR,FGFR,Apoptosis