Bioactivity:

Sprengerinin C exerts anti-tumorigenic effects in hepatocellular carcinoma via inhibition of proliferation and angiogenesis and induction of apoptosis, it can strongly suppress tumor angiogenesis in human umbilical vein endothelial cells, it blocks vascul

CAS nr:

88861-91-0

Purity:

98%

Molecular Weight:

855

SMILES:

C[C@H]1C2[C@H](C[C@H]3[C@@H]4CC=C5C[C@H](CC[C@]5(C)[C@H]4CC[C@]23C)O[C@@H]2O[C@H](CO)[C@@H](O[C@@H]3OC[C@@H](O)[C@H](O)[C@H]3O)[C@H](O)[C@H]2O[C@@H]2O[C@@H](C)[C@H](O)[C@@H](O)[C@H]2O)O[C@]11CC[C@@H](C)CO1

Formula:

C44H70O16

Pathway:

Tyrosine Kinase/Adaptors,Angiogenesis,PI3K/Akt/mTOR signaling,Immunology/Inflammation,PI3K/Akt/mTOR signaling,PI3K/Akt/mTOR signaling,MAPK,Cytoskeletal Signaling,Apoptosis,Immunology/Inflammation

Target:

VEGFR,VEGFR,mTOR,ROS,PI3K,Akt,p38 MAPK,Akt,p53,NADPH-oxidase