Bioactivity:

1. Euphorbia factor L1 can enhance the ATP hydrolysis activity of ABCB1 stimulated by verapamil. 2. Euphorbia factor L1 inhibits the efflux of ABCB1 in KBv200 and MCF-7/adr cells, does not downregulate their expression either in mRNA or protein level.

CAS nr:

76376-43-7

Purity:

98%

Molecular Weight:

552,66

SMILES:

C[C@H]1C[C@@]2(OC(C)=O)[C@H]([C@H]1OC(=O)Cc1ccccc1)[C@@H](OC(C)=O)[C@@]1(CO1)CC[C@H]1[C@@H](\C=C(C)\C2=O)C1(C)C

Formula:

C32H40O8

Pathway:

Neuroscience,Membrane transporter/Ion channel,Apoptosis

Target:

P-gp,P-gp,Apoptosis