Bioactivity:

OTS514 is a potent TOPK inhibitor. OTS514 exhibits a growth-suppressive effect on small cell lung cancer. OTS514 effectively suppressed the growth of SCLC cell lines (IC50: 0.4 ~ 42.6 nM). Treatment with OTS514 suppressed forkhead box protein M1 (FOXM1) a

CAS nr:

1338540-63-8

Purity:

98%

Molecular Weight:

364,46

SMILES:

CC(CN)c(cc1)ccc1-c(c(-c1c2scc1)c(c(C)c1)NC2=O)c1O

Formula:

C21H20N2O2S

Pathway:

MAPK,Apoptosis

Target:

TOPK,Apoptosis