Bioactivity:

Ku-60019 is a potent, reversible inhibitor of ATM kinase (IC50: 6.3 nM). It is much less effective or without effect against a panel of 229 other kinases.

CAS nr:

925701-49-1

Purity:

98%

Molecular Weight:

547,67

SMILES:

C[C@H]1CN(CC(=O)Nc2ccc3Sc4c(Cc3c2)cccc4-c2cc(=O)cc(o2)N2CCOCC2)C[C@@H](C)O1

Formula:

C30H33N3O5S

Pathway:

PI3K/Akt/mTOR signaling,DNA Damage/DNA Repair

Target:

ATM/ATR,ATM/ATR