Bioactivity:

Masitinib is a tyrosine-kinase inhibitor used in the treatment of mast cell tumors in animals, specifically dogs. Since its introduction in November 2008 it has been distributed under the commercial name Masivet. It has been available in Europe since the

CAS nr:

790299-79-5

Purity:

98%

Molecular Weight:

498,64

SMILES:

CN1CCN(Cc2ccc(cc2)C(=O)Nc2ccc(C)c(Nc3nc(cs3)-c3cccnc3)c2)CC1

Formula:

C28H30N6OS

Pathway:

Angiogenesis,Tyrosine Kinase/Adaptors,Angiogenesis,Tyrosine Kinase/Adaptors,Angiogenesis,Tyrosine Kinase/Adaptors,Angiogenesis,Tyrosine Kinase/Adaptors,Cytoskeletal Signaling,Tyrosine Kinase/Adaptors,Apoptosis,Tyrosine Kinase/Adaptors,Tyrosine Kinase/Adaptors,Angiogenesis,Tyrosine Kinase/Adaptors,Cytoskeletal Signaling

Target:

PDGFR,PDGFR,FGFR,Src,Src,FGFR,FAK,FAK,FAK,c-Fms,Apoptosis,Hck,c-Kit,Bcr-Abl,Bcr-Abl,Bcr-Abl