Bioactivity:

PIK-90, a DNA-PK and PI3K inhibitor, suppresses p110_( IC50=11 nM), p110_(IC50=18 nM) and DNA-PK(IC50=13 nM) .

CAS nr:

677338-12-4

Purity:

98%

Molecular Weight:

351,36

SMILES:

COc1ccc2C3=NCCN3C(NC(=O)c3cccnc3)=Nc2c1OC

Formula:

C18H17N5O3

Pathway:

PI3K/Akt/mTOR signaling,DNA Damage/DNA Repair,PI3K/Akt/mTOR signaling

Target:

PI3K,DNA-PK,DNA-PK