Bioactivity:

TG 100572 Hydrochloride is a inhibitor of multi-targeted kinase which inhibits receptor tyrosine kinases and Src kinases(IC50s of 2, 7, 2, 16, 13, 5, 0.5, 6, 0.1, 0.4, 1, 0.2 nM for VEGFR1, VEGFR2, FGFR1, FGFR2, PDGFR_, Fgr, Fyn, Hck, Lck, Lyn, Src, Yes,

CAS nr:

867331-64-4

Purity:

98%

Molecular Weight:

512,43

SMILES:

ClC1=CC=C(O)C=C1C2=CC(C)=C(N=C(NC(C=C3)=CC=C3OCCN4CCCC4)N=N5)C5=C2.Cl

Formula:

C26H27Cl2N5O2

Pathway:

Angiogenesis,Tyrosine Kinase/Adaptors,Tyrosine Kinase/Adaptors,Angiogenesis,Angiogenesis,Tyrosine Kinase/Adaptors,Angiogenesis,Tyrosine Kinase/Adaptors

Target:

PDGFR,PDGFR,VEGFR,VEGFR,FGFR,Src,Src,FGFR