Bioactivity:

TAK-044 is an endotheliin receptor antagonist that prevents and reverses the development of carbon tetrachloride induced cirrhosis in rats. TAK-044 showed a protective effect on neuronal activity in vitro hypoxic glucose deprivation model of stroke.

CAS nr:

157380-72-8

Purity:

98%

Molecular Weight:

971,99

SMILES:

O=C(N1CCN(C2=CC=CC=C2)CC1)C[C@H](C(N[C@@H](CC([O-])=O)C(N[C@H](C3=CC=CS3)C(N[C@H](CC(C)C)C(N[C@@H]4CC5=CNC6=C5C=CC=C6)=O)=O)=O)=O)NC([C@@H](CC([O-])=O)NC4=O)=O.[Na+].[Na+]

Formula:

C45H51N9Na2O11S

Pathway:

Target: