Bioactivity:

GLPG2451 is a cystic fibrosis transmembrane conductance regulator (CFTR) potentiator. It�effectively potentiates low temperature rescued F508del CFTR (EC50: 11.1 nM).

CAS nr:

2055015-61-5

Purity:

98%

Molecular Weight:

419,38

SMILES:

O=S(C1=CC=C(OC(F)(F)F)C=C1)(C2=CN=C(C(NC[C@@H](O)C)=O)C(N)=C2)=O

Formula:

C16H16F3N3O5S

Pathway:

Proteases/Proteasome

Target:

Cysteine Protease