Bioactivity:

Bractoppin is a drug-like inhibitor of phosphopeptide recognition by the human BRCA1 tandem (t)BRCT domain (IC50 = 0.074 _M), which selectively inhibits substrate binding with nanomolar potency in vitro. Structure-activity exploration suggests that Bracto

CAS nr:

2290527-07-8

Purity:

98%

Molecular Weight:

414,47

SMILES:

O=C(N1CCN(CC2=CC=CC=C2F)CC1)C3=CC=C4NC(C5=CC=CC=C5)=NC4=C3

Formula:

C25H23FN4O

Pathway:

Others,DNA Damage/DNA Repair,Cell Cycle/Checkpoint

Target:

Others,DNA/RNA Synthesis,DNA/RNA Synthesis