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TargetMol Chemicals

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TargetMol Chemicals Inc. specializes in products and services that serve the research needs of chemical and biological scientists worldwide. With a client base in 40+ countries, TargetMol has evolved into one of the biggest global research suppliers for compound libraries and small molecule compounds.

TargetMol diligently updates and offers over 170 types of compound libraries and a wide range of high-quality research chemicals, including inhibitors, activators, natural products, peptides, antibodies , and novel life-science kits for laboratory and scientific use. In addition, their lab allows them to conduct CADD (computer-aided drug design) and chemical synthesis to meet the customization needs of their clients.

With TargetMol’s high-quality products & services, fast & efficient global supply chain and professional technical support, TargetMol believes they will help you shorten your research process and yield a more successful result.

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AZD-1480 T3069

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Specifications

1mg/5mg/10mg/25mg/50mg/100mg

Bioactivity:

AZD1480 is a novel ATP-competitive JAK2 inhibitor (IC50: 0.26 nM), selectivity act against Tyk2 and JAK3, and to a smaller extent against JAK1. AZD1480 has been used in trials studying the treatment of Solid Malignancies, Post-Polycythaemia Vera, Primary

CAS nr:

935666-88-9

Purity:

98%

Molecular Weight:

348,77

SMILES:

C[C@H](Nc1ncc(Cl)c(Nc2cc(C)[nH]n2)n1)c1ncc(F)cn1

Formula:

C14H14ClFN8

Pathway:

Angiogenesis,JAK/STAT signaling,Chromatin/Epigenetic,Stem Cells

Target:

JAK,JAK,JAK,JAK