Bioactivity:

MT 63-78 is a specific and effective direct AMPK activator (EC50: 25 _M). MT 63-78 blocks prostate cancer growth by inhibiting the lipogenesis and mTORC1 pathways. MT 63-78 has antitumor effects. MT 63�78 also causes cell mitotic arrest and apoptosis.

CAS nr:

1179347-65-9

Purity:

98%

Molecular Weight:

326,35

SMILES:

Oc1cccc(O)c1-c1ccc(cc1)-c1ccc2[nH]cc(C#N)c2c1

Formula:

C21H14N2O2

Pathway:

PI3K/Akt/mTOR signaling,PI3K/Akt/mTOR signaling,Apoptosis

Target:

AMPK,mTOR,Apoptosis